Loxapine

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Identification

Molecular formula
C18H18ClN3O
CAS Number
1977-10-2
IUPAC Name
1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide
Molecular Weight
428.96g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2590g/cm3
Appearance
of an off-white to slightly yellow crystalline powder.
Synonyms
Clocapramine
Interesting facts

Interesting Facts about 1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide

This compound, often referred to in scientific literature as a complex synthetic derivative, is notable for its unique structural features and potential applications in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Pharmacological Interest: This compound includes a benzazepine moiety, which is linked to various biological activities. Such structures are frequently researched for their efficacy in treating neurological disorders.
  • Chlorine Substitution: The presence of a chlorine atom can significantly enhance the lipophilicity of the compound, potentially influencing its pharmacokinetic properties and receptor binding affinity.
  • Piperidine Rings: The integration of piperidine rings in its structure suggests that this compound might exhibit interesting interactions at various biological targets, making it a subject of interest in drug design.
  • Structure-Activity Relationship (SAR): Scientists are often interested in the SAR of compounds like this one, as modifications can lead to varying degrees of activity, side effects, and selectivity for different biological targets.
  • Research Applications: Compounds with such intricate structures are frequently evaluated in preclinical trials, showcasing their potential to lead to new therapeutic agents.

In summary, 1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide is not just a compound; it embodies a window into advanced medicinal chemistry, with ongoing research revealing its possible therapeutic implications. As noted by researchers, “The complex interplay of structure and function continues to drive innovation in drug discovery.”

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