Floxuridine

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Identification

Molecular formula
C9H11FN2O5
CAS Number
50-91-9
IUPAC Name
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-6-fluoro-pyrimidine-2,4-dione
Molecular Weight
246.19g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.8520g/cm3
Interesting facts

Interesting Facts about 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-6-fluoro-pyrimidine-2,4-dione

This compound represents a fascinating intersection of carbohydrate chemistry and nucleobase structure, combining elements that are essential in biological systems.

  • Bioactivity: 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-6-fluoro-pyrimidine-2,4-dione is noted for its potential bioactivity, particularly in medicinal chemistry where it may exhibit antiviral and anticancer properties.
  • Structural Features: The compound's structure features a pyrimidine ring, which is a key scaffold in many biologically active compounds, as well as a tetrahydrofuran moiety that can influence its biological interactions.
  • Fluorine Substitution: The presence of a fluorine atom is particularly interesting; fluorine can enhance the stability and lipophilicity of the compound, potentially improving its pharmacokinetic properties in biological systems.
  • Synthesis Challenges: The synthesis of this compound can be quite challenging due to the delicate balance of functional groups involved, with specific conditions needed to maintain the integrity of each component during synthesis.

As quoted by many chemists, "Chemistry is the art of manipulating molecules to create something unexpected." This compound serves as a perfect example of how intricate molecular designs can lead to novel compounds with promising biological applications.

Further studies into the mechanisms of action and potential therapeutic applications could reveal even more about this intriguing chemical, highlighting the interconnectedness of various fields within chemistry.

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