Berbérine

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Identification

Molecular formula
C20H20NO4
CAS Number
2086-83-1
IUPAC Name
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline
Molecular Weight
336.38g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3768g/cm3
Synonyms
papaverine
Interesting facts

Interesting Facts about 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline

This intriguing compound is a member of the isoquinoline family, which is renowned for its diverse bioactivity and potential medicinal applications. Isoquinolines have been studied extensively due to their presence in various natural products and their ability to function as pharmacophores in drug design.

Structural Features

  • Dimethoxy Group: The presence of two methoxy groups in the isoquinoline structure enhances its lipophilicity and helps in molecular interactions, contributing significantly to its biological activity.
  • Substituted Phenyl Ring: The 3,4-dimethoxyphenyl substitution provides additional electron-donating properties, which can facilitate interactions with biological receptors.

Potential Applications

This compound has garnered attention in various areas of research, including:

  • Pharmacology: Its complex structure suggests potential anti-cancer, anti-inflammatory, and analgesic properties.
  • Neuroscience: Isoquinoline derivatives are often investigated for their neuroprotective effects and possible use in the treatment of neurodegenerative diseases.

Research Insights

Studies indicate that compounds like 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline may function through mechanisms such as:

  • Modulation of neurotransmitter systems
  • Inhibition of specific enzymes related to disease pathways
  • Interference with cell cycle progression in cancer cells

In the words of a researcher exploring isoquinoline derivatives: "The intricate architecture of these compounds opens avenues for novel therapeutic strategies that often extend beyond traditional pharmacology."

Overall, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline encapsulates the dynamic potential of synthetic organic compounds in contemporary chemical research. Its structural uniqueness and potential applications make it a fascinating subject for ongoing studies in both medicinal chemistry and biochemistry.

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