Bupropion

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Identification

Molecular formula
C13H17ClNO
CAS Number
34841-39-9
IUPAC Name
1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one
Molecular Weight
239.74g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.0132g/cm3
Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one

This compound is a fascinating example of the diversity found within organic chemistry, particularly in the realm of psychoactive substances. Its structure suggests it belongs to a class of compounds that may influence the central nervous system due to its unique pharmacophore configuration.

Key Features

  • Fluorine Substitution: The presence of a fluorine atom in the para position of the phenyl ring can significantly alter the compound’s biological activity, impacting its potency and metabolic stability.
  • 3-Azabicyclo Framework: The bicyclic structure is not only intriguing from a synthetic chemistry standpoint but also plays a role in the compound's interaction with neuronal receptors. Bicyclic compounds are often pivotal in drug design, providing a window into the synergy between structure and function.
  • Potential Applications: Compounds like this one are of great interest for their potential applications in treating neurological disorders, including but not limited to anxiety and depression. Research continues to uncover their role in neurochemistry.

Scientific Insights

As noted by researchers in the field, "The delicate balance of molecular interactions determines the efficacy of compounds in neurological therapies." This highlights the importance of the compound's spatial arrangement, which can be fine-tuned through synthetic approaches.

Additionally, the stereochemical aspects of this compound could lead to enantiomers with vastly different biological profiles, which is a fascinating consideration for drug development. The exploration of these variations represents a significant area of ongoing research, as scientists aim to refine therapeutic profiles while minimizing side effects.

In conclusion, 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one embodies a rich tapestry of opportunities for discovery in chemical and pharmaceutical sciences, serving as a reminder of the intricate dance between structure and function in organic chemistry.

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