Fluoro-Metopon
- Molecular formula
- C26H28FN3O
- CAS Number
- 255823-97-1
- IUPAC Name
- 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidyl]benzimidazol-2-amine
- Molecular Weight
- 516.61g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.2430g/cm3
- Synonyms
- astemizole
Identification
Exploring 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidyl]benzimidazol-2-amine
This fascinating compound, often abbreviated in various ways, belongs to the group of benzimidazoles, which are notable for their diverse pharmacological profiles. As a scientist, understanding this compound unveils several interesting aspects:
- Versatile Pharmacophore: The benzimidazole ring system is recognized for its **bioactive potential**. Compounds containing this structure often exhibit activities, including anti-inflammatory and anti-cancer properties.
- Fluorine Impact: The inclusion of the fluorine atom in its structure can greatly enhance the compound's **lipophilicity** (fat affinity) and **metabolic stability**. This feature is a result of fluorine's unique ability to alter electronic properties.
- Piperidine Linkage: The piperidine moiety contributes significantly to the compound’s **binding affinity** to various receptors, such as those in the central nervous system. This makes compounds like this appealing for potential therapeutic applications in treating psychiatric or neurological disorders.
- Substituent Effects: The presence of methoxy groups and phenyl rings not only adds to the overall complexity of the molecule but may also impact its **interaction with biological targets**. These groups are known to participate in π-π stacking and hydrophobic interactions.
As with many complex organic compounds, the study of 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidyl]benzimidazol-2-amine offers an opportunity for discovery not just in terms of medicinal chemistry but also in **theoretical modeling** and **synthesis methods**. The exploration of such compounds contributes to the broader understanding of drug design and the ways in which molecular structure correlates with biological function.
"Chemistry is the essence of life itself." Understanding compounds like this one can lead to advancements in medicine and technology that improve our quality of life.