4-Iodo-2,5-dimethoxyamphetamine (DOI)

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Identification

Molecular formula
C13H20INO2
CAS Number
50745-43-2
IUPAC Name
1-(4-iodophenyl)-N-isopropyl-propan-2-amine
Molecular Weight
307.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5120g/cm3
Appearance
4-Iodo-2,5-dimethoxyamphetamine is typically found in crystalline powder form, appearing as white to off-white crystals. The compound may also be synthesized and used in solution form for research purposes.
Synonyms
iofetamine
Interesting facts

Interesting Facts about 1-(4-Iodophenyl)-N-isopropyl-propan-2-amine

1-(4-Iodophenyl)-N-isopropyl-propan-2-amine, often referred to as a compound of interest in medicinal chemistry, stands out due to several compelling features:

  • Pharmacological Potential: This compound is part of a class of molecules that may have implications in developing new therapeutic agents, potentially targeting different neurological conditions.
  • Structural Insights: The presence of an iodo substituent (4-iodophenyl) on the phenyl ring may contribute to its unique properties, affecting both its reactivity and biological activity.
  • Synthesis Challenges: The synthesis of this compound may involve intricate multi-step processes, often requiring advanced techniques in organic chemistry.
  • Research Relevance: Compounds with similar structures are frequently studied for their interactions with neurotransmitter systems, highlighting their relevance in neuropharmacology.
  • Analytical Techniques: Scientists utilize various analytical techniques, such as NMR and mass spectrometry, to elucidate the structural properties and confirm the successful synthesis of such compounds.

This compound serves as an excellent example of how small changes in molecular structure can lead to significant variations in biological activity. As noted by renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." Research into compounds like 1-(4-Iodophenyl)-N-isopropyl-propan-2-amine continues to fuel innovation and discovery in the ever-evolving field of medicinal chemistry.

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