1-[(5-chloro-1-naphthyl)sulfonyl]-1,4-diazepane

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Identification

Molecular formula
C16H19ClN2O2S
CAS Number
887268-92-4
IUPAC Name
1-[(5-chloro-1-naphthyl)sulfonyl]-1,4-diazepane
Molecular Weight
342.86g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3190g/cm3
Synonyms
ML-9 free base
Interesting facts

Interesting Facts about 1-[(5-Chloro-1-naphthyl)sulfonyl]-1,4-diazepane

1-[(5-Chloro-1-naphthyl)sulfonyl]-1,4-diazepane is an intriguing compound that has garnered interest in various fields, particularly in medicinal chemistry. Here are some fascinating insights:

  • Pharmacological Potential: This compound has been studied for its potential therapeutic applications, owing to the presence of the 1naphthyl group, which is known for its biological activity. It can act on different biological targets, suggesting its role in drug development.
  • Sulfonamide Moiety: The sulfonyl functional group enhances the compound’s properties, which might improve its interaction with target molecules, thereby influencing its efficacy as a drug candidate.
  • Diazepane Ring: The diazepane structure introduces unique steric and electronic characteristics, making it a versatile scaffold for structural modifications. Scientists often explore diazepane derivatives for their varying pharmacological effects.
  • Chlorine Atom: The incorporation of the chlorine atom is significant as it often enhances the lipophilicity of the compound, which can improve membrane permeability and, consequently, the bioavailability of the drug.
  • Structure-Activity Relationship (SAR): Understanding SAR is crucial for optimizing the biological activity of this compound. Modifications to either the naphthyl or diazepane ring can lead to the discovery of more potent analogs.

As researchers continue to investigate this compound, its potential in the development of new therapeutic agents could illuminate new treatment pathways for various health conditions. A quote often heard in scientific circles is, “The next breakthrough may lie within the next molecule we explore.” 1-[(5-Chloro-1-naphthyl)sulfonyl]-1,4-diazepane exemplifies how seemingly straightforward changes to molecular structure can lead to significant advancements in pharmaceutical research.

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