Combretastatin A-4

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Identification

Molecular formula
C18H20NO5
CAS Number
117048-59-6
IUPAC Name
1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]-3-(4-methoxyphenyl)prop-2-en-1-one
Molecular Weight
316.35g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2000g/cm3
Synonyms
DTXSID901043264
Interesting facts

Interesting Facts About 1-[6-[2-(Dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]-3-(4-methoxyphenyl)prop-2-en-1-one

This compound, often referred to in the context of medicinal chemistry, features a fascinating structure that highlights the intersection of organic synthesis and pharmacology. Here are some captivating details about its characteristics and potential uses:

  • Structural Complexity: The elaborate structure contains both benzofuran and dimethoxy groups. This complexity may contribute to its biological activity by influencing how it interacts with various biological targets.
  • Pharmacological Potential: Compounds with benzofuran derivatives are often investigated for their pharmacological properties, including anti-inflammatory, analgesic, and anticancer activities. This compound is a subject of interest in studies aiming to understand its therapeutic profiles.
  • Role of Dimethylamino Group: The presence of the dimethylamino group suggests that this compound may exhibit enhanced lipophilicity, potentially improving its ability to cross cell membranes. This aspect is crucial for drug delivery and efficacy.
  • Research Applications: Due to its unique chemical structure, this compound can be a valuable tool in medicinal chemistry for synthesizing related compounds or exploring structure-activity relationships.
  • In Silico Studies: Researchers often employ computational methods to predict the behavior of such compounds in biological systems, facilitating the optimization of lead compounds in drug discovery.

In summary, 1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]-3-(4-methoxyphenyl)prop-2-en-1-one stands as an intriguing molecular candidate for further research. Scientists are continuously exploring its properties to unlock new therapeutic avenues.

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