1-Butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea

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Identification

Molecular formula
C12H18N2O4S
CAS Number
100725-06-2
IUPAC Name
1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonyl-urea
Molecular Weight
315.39g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2500g/cm3
Synonyms
4-Hydroxytolbutamide
Interesting facts

Interesting Facts about 1-Butyl-3-[4-(hydroxymethyl)phenyl]sulfonyl-urea

1-Butyl-3-[4-(hydroxymethyl)phenyl]sulfonyl-urea is a fascinating compound with unique properties and applications. As a scientist or chemistry student, understanding this compound can offer intriguing insights into its functionality and significance. Here are some notable facts:

  • Versatile Applications: This compound is primarily explored for its therapeutic potential, especially in medicinal chemistry. The sulfonylurea moiety is renowned for its role in treating Type 2 diabetes by enhancing insulin secretion.
  • Molecular Interactions: The presence of the hydroxymethyl group in the phenyl ring allows for hydrogen bonding, which can increase the compound's interactions with biological targets, enhancing its efficacy.
  • Synthetic Pathways: The synthesis of this compound can involve multi-step organic reactions, allowing for exploration in synthetic chemistry. Scientists often focus on optimizing reaction conditions to achieve higher yields and purity.
  • Potential for Customization: The butyl group provides a hydrophobic character that can influence the compound’s lipophilicity, potentially impacting its absorption and distribution in living systems. Altering this alkyl chain could lead to new derivatives with improved properties.
  • Structural Analysis: Analyzing the compound’s structure through spectroscopic methods like NMR and IR can provide insights into functional groups’ behavior and interactions within biological systems.

In summary, 1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonyl-urea is more than just a chemical formula; it represents a bridge between organic chemistry and pharmaceutical applications, making it a compelling subject for research and study.

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