1-Hydroxypyridine-2(1H)-thione

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Identification

Molecular formula
C5H5NOS
CAS Number
1121-31-9
IUPAC Name
1-hydroxypyridine-2-thione
Molecular Weight
127.17g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4000g/cm3
Synonyms
pyrithione
Interesting facts

Interesting Facts about 1-Hydroxypyridine-2-thione

1-hydroxypyridine-2-thione, a fascinating compound in the realm of heterocyclic chemistry, showcases the intriguing interplay between nitrogen, sulfur, and oxygen within its structure. Here are some compelling aspects of this compound:

  • Bioactivity: This compound is known for its diverse biological activities, which include antimicrobial and potentially antifungal properties, making it a subject of interest in pharmaceutical research.
  • Coordination Chemistry: 1-hydroxypyridine-2-thione acts as a bidentate ligand, capable of forming stable complexes with transition metals. This feature is vital in catalytic processes and material science.
  • Synthesis Versatility: The compound can be synthesized through various methods, often involving the modification of pyridine derivatives. Its versatility in synthesis opens up pathways for tailored functionalizations.
  • Analytical Applications: Its unique functional groups allow for its use in analytical techniques, particularly in the detection of metal ions, due to its chelating abilities.
  • Research Relevance: Ongoing studies explore its role in developing new materials and chemical sensors, highlighting its significance in contemporary chemistry.

The study of 1-hydroxypyridine-2-thione not only enhances our understanding of pyridine chemistry but also underscores the importance of sulfur-containing compounds in biological and industrial applications. As a student or scientist, one might find that the synergy of its properties provides a fertile ground for innovation and discovery.

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