Brinzolamide

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Identification

Molecular formula
C12H21BrClN7O2S3
CAS Number
138890-62-7
IUPAC Name
1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Molecular Weight
383.43g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.7383g/cm3
Synonyms
hydroflumethiazide
Interesting facts

Interesting Facts about 1,1-Dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide

This compound is a fascinating member of the benzothiadiazine family, a group known for its unique structures and diverse applications in medicinal chemistry. Here are some noteworthy aspects of this compound:

  • Pharmaceutical Relevance: Benzothiadiazines are often evaluated for their potential as pharmacological agents, notably as diuretics and antihypertensives.
  • Interesting Substituents: The presence of a trifluoromethyl group can significantly influence the biological properties of compounds, enhancing their lipophilicity and metabolic stability.
  • Multifunctionality: This compound's sulfonamide group may contribute to its effectiveness in medical applications, as sulfonamides are often used as antibiotics and antiviral agents.
  • Structure-Activity Relationship (SAR): Understanding the structure of this compound allows researchers to predict its biological activity and develop derivatives that may be more effective in targeting specific biological pathways.
  • Synthetic Pathways: The synthesis of such complex compounds showcases the ingenuity of modern organic chemistry and the development of innovative strategies to create highly specific molecular structures.

Combining these features, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide represents a compelling area of study for chemists interested in drug design and development. As Albert Einstein famously said, "Pure mathematics is, in its way, the poetry of logical ideas." In a similar vein, the synthesis and study of complex chemical compounds can be seen as a form of artistic expression within the realm of scientific inquiry.

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