Tacrine

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Identification

Molecular formula
C13H14N2
CAS Number
321-64-2
IUPAC Name
1,2,3,4-tetrahydroacridin-9-amine
Molecular Weight
198.27g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1844g/cm3
Synonyms
Tacrine
Interesting facts

Interesting Facts About 1,2,3,4-Tetrahydroacridin-9-amine

1,2,3,4-Tetrahydroacridin-9-amine is a fascinating compound that has garnered attention in the fields of medicinal chemistry and neuropharmacology. Below are some intriguing insights into its characteristics and potential applications:

  • Pharmacological Interest: This compound has been studied for its potential neuroprotective properties. Some research suggests it may help in the treatment of neurodegenerative diseases, such as Alzheimer’s, due to its ability to enhance memory and cognitive function.
  • Structural Features: The structure of 1,2,3,4-tetrahydroacridin-9-amine includes a polycyclic ring system known as acridine, which is known for its planar structure and ability to intercalate with DNA. This feature is significant in understanding its biological interactions.
  • Mechanism of Action: Studies hint that this compound could influence the cholinergic system, enhancing acetylcholine activity, a crucial neurotransmitter involved in learning and memory processes.
  • Synthesis: The synthesis typically involves various organic reactions, which can be modified to yield different derivatives. This flexibility in synthesis allows researchers to explore a range of analogs with potentially diverse biological activities.
  • Potential Side Effects: While promising, it is essential for researchers to study any side effects or toxicity associated with the compound to ensure its safety for therapeutic use.

In summary, 1,2,3,4-tetrahydroacridin-9-amine is much more than just a chemical compound; it opens doors to understanding complex neurological mechanisms and highlights the intricate relationship between structure and biological function. The exploration of its properties and potential therapeutic applications continues to be an exciting area of research!

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