Cimetidine

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Identification

Molecular formula
C13H16N6O
CAS Number
51481-61-9
IUPAC Name
1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea;dihydrochloride
Molecular Weight
252.34g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3900g/cm3
Synonyms
Imidocarb hydrochloride
Interesting facts

Interesting Facts about 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea; dihydrochloride

This compound, known as 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea; dihydrochloride, is a fascinating example of a molecule that merges both medicinal and synthetic chemistry. Here are some engaging insights about this compound:

  • Biological Relevance: This compound has shown potential in biomedical research, particularly in the field of cancer therapeutics. Its structure suggests that it could interact with specific cellular targets, making it a candidate for further investigations in drug development.
  • Urea Derivatives: The urea functional group in this compound plays a crucial role in medicinal chemistry. Urea and its derivatives are known for their ability to mimic peptide bonds, leading to improved selectivity and efficacy in therapeutic applications.
  • Synthetic Versatility: The synthetic route to this compound involves a combination of organic reactions that highlight the versatility of urea chemistry. Chemists can employ various strategies to modify the phenyl and imidazole components, thus creating a diversity of derivatives that can be tailored for specific functions.
  • Imidazole Influence: The presence of the 4,5-dihydro-1H-imidazol-2-yl group enhances the compound's potential for biological interaction. Imidazole is a common motif in pharmaceuticals, often contributing to enzyme inhibition and receptor binding activities.
  • Overcoming Resistance: Given its unique structure, this compound may provide insights into overcoming drug resistance in tumors. Research into similar diamine derivatives has yielded important lessons in modifying drugs that can effectively bypass established resistance mechanisms.

In summary, 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea; dihydrochloride is not just a multi-functional compound; it exemplifies the intersection of theoretical chemistry and practical application, showcasing the endless possibilities inherent in organic synthesis and medicinal chemistry.

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