15-Hydroxyicosatetraenoic acid

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Identification

Molecular formula
C20H32O3
CAS Number
67701-06-4
IUPAC Name
15-hydroxyicosa-8,11,13-trienoic acid
Molecular Weight
318.47g/mol
Melting Point
compared to saturated fatty acids.
Boiling Point
(Celsius)
Density
0.9270g/cm3
Synonyms
15(S)-HETRE
Interesting facts

Interesting Facts about 15-Hydroxyicosa-8,11,13-trienoic Acid

15-Hydroxyicosa-8,11,13-trienoic acid, often abbreviated as 15-Hydroxy-icosatrienoic acid, is a fascinating compound notable for its role in biochemical processes. Here are some engaging facts about this intriguing fatty acid:

  • Endocannabinoid System: This compound is a part of the endocannabinoid system; it has been suggested to have various effects on both central nervous system functions and peripheral processes.
  • Biological Significance: 15-Hydroxyicosa-8,11,13-trienoic acid is generated from the metabolism of the polyunsaturated fatty acid arachidonic acid via the action of lipoxygenase enzymes. Its presence is significant in the regulation of inflammatory responses.
  • Potential Therapeutic Uses: Research has indicated that compounds like 15-Hydroxyicosa-8,11,13-trienoic acid may have therapeutic potential in treating diseases related to inflammation, pain, and other metabolic disorders.
  • Structure-Activity Relationship: Understanding the structural characteristics of this compound is crucial as it helps in the development of analogs that might enhance its biological efficacy or reduce potential side effects.
  • Natural Sources: This compound can be derived from various natural sources, particularly in processes involving the metabolism of dietary fatty acids. Its occurrence in certain tissues emphasizes the importance of dietary fats in health and disease.

In summary, 15-Hydroxyicosa-8,11,13-trienoic acid is much more than just a chemical; it's a key player in the intricate web of biological systems, potentially offering insights into new therapeutic avenues. As stated by researchers, "Understanding the functionality of such compounds may revolutionize our approaches to health and disease management."

Continued research into this compound can unveil new pathways for understanding metabolic functions and may pave the way for innovations in drug design and development.

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