Dexamethasone

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Identification

Molecular formula
C22H29FO5
CAS Number
50-02-2
IUPAC Name
17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular Weight
392.47g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3100g/cm3
Appearance
may vary slightly depending on its form and purity.
Synonyms
Fluoromethalone
Interesting facts

Interesting Facts about 17-Acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

This unique compound, often referred to in research settings, has garnered attention for a variety of compelling reasons. Here are some notable aspects:

  • Pharmaceutical Applications: This compound plays a crucial role in the development of corticosteroids, which are widely used in medicine for their anti-inflammatory and immunosuppressive properties.
  • Fluorine Substitution: The presence of the fluorine atom enhances the metabolic stability of the compound, making it a subject of interest for medicinal chemists looking to improve drug efficacy.
  • Multi-Hydroxyl Groups: The dihydroxy groups in its structure contribute to the compound's potential interactions in biological systems, which can influence its pharmacological activity.
  • Cyclic Structures: The cyclopenta[a]phenanthrene framework provides interesting stereochemistry that can affect how the compound interacts with biological targets.

In the words of one researcher, "The intricate structure of this compound is a testament to the fascinating world of organic chemistry and highlights the importance of functional groups in drug design."
As a student of chemistry, studying compounds like this offers insight not only into organic synthesis but also into potential therapeutic pathways, revealing how modifications can lead to significant changes in biological activity.

Overall, the detailed examination of compounds like 17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one opens up avenues for innovative research and pharmaceutical advancements.

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