1-Indole-3-(4-piperidyl)ketone

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Identification

Molecular formula
C14H16N2O
CAS Number
122-91-0
IUPAC Name
1H-indol-3-yl(4-piperidyl)methanone
Molecular Weight
230.30g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2210g/cm3
Synonyms
3-Isonipecotylindole
Interesting facts

Interesting Facts about 1H-indol-3-yl(4-piperidyl)methanone

The compound 1H-indol-3-yl(4-piperidyl)methanone is an intriguing structure that merges the indole and piperidine moieties, creating a unique compound with potential applications in medicinal chemistry. Here are some notable aspects of this fascinating compound:

  • Versatile Pharmacophore: The indole ring is a common feature in many biologically active compounds, including several pharmaceuticals. Its presence is often associated with antidepressant and anti-cancer activities.
  • Piperidine Integration: The 4-piperidyl group contributes to its overall pharmacological profile. Piperidine derivatives are known to exhibit a range of biological activities, making this compound a candidate for further research.
  • Potential Therapeutic Uses: Research suggests that compounds containing both indole and piperidine structures may possess anti-inflammatory, antipsychotic, and neuroprotective properties.
  • Structure-Activity Relationship (SAR): The combination of these two structural frameworks allows for the exploration of SAR, which can ultimately help chemists design more effective drugs based on observed biological activities.
  • Natural Occurrence: Indole derivatives are frequently found in numerous natural products, while piperidine is often encountered in alkaloids, further enhancing the ecological and pharmacological relevance of this compound.

In summary, 1H-indol-3-yl(4-piperidyl)methanone stands as a testament to the intricate designs of organic chemistry, where small changes in structure can lead to significant variations in biological activity. As scientists continue to explore compounds like this, we move closer to unlocking new avenues for drug development and health improvement.

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