Fulvestrant

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Identification

Molecular formula
C32H47F1N1O1
CAS Number
129453-61-8
IUPAC Name
(1S,14S,17R)-17-ethynyl-7-(4-fluorophenyl)-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
Molecular Weight
606.77g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.0460g/cm3
Interesting facts

Interesting Facts about (1S,14S,17R)-17-ethynyl-7-(4-fluorophenyl)-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol

This complex compound is a fascinating example of structural diversity in organic chemistry, showcasing intricate molecular architecture. Here are some captivating insights about this compound:

  • Stereochemistry: The specific stereochemical configuration denoted by (1S,14S,17R) plays a crucial role in determining the compound's biological activity and interactions. Stereochemistry helps scientists understand how the spatial arrangement of atoms influences the compound's properties.
  • Fluorine Substitution: The presence of a 4-fluorophenyl group is particularly interesting. Fluorinated compounds often exhibit enhanced pharmacological properties, such as improved metabolic stability and bioactivity, making this compound a subject of study in medicinal chemistry.
  • Complex Framework: The pentacyclic structure indicates a unique arrangement of carbon atoms that can lend itself to interesting chemical properties. This level of complexity is often observed in naturally occurring alkaloids and can lead to unique interactions in biological systems.
  • Potential Applications: Given the intricate structure and functional groups, this compound could have potential applications in pharmaceutical development. Researchers may investigate its activity against various biological targets.
  • Cyclic Compounds: Compounds with cyclic structures, such as this one, can exhibit unique conformational isomerisms that impact their reactivity and interaction with other molecules. Understanding these can open pathways for designing new compounds with desired properties.
  • Research Significance: As a member of a class of compounds with intriguing structures, studying this compound can provide insights into synthetic methodologies and strategies for creating complex molecules from simpler precursors.

In summary, the (1S,14S,17R)-17-ethynyl-7-(4-fluorophenyl)-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol compound exemplifies the extraordinary variety and potential of organic compounds in the realm of chemistry, inviting further exploration and discovery.

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