Indometacin

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Identification

Molecular formula
C19H16ClNO4
CAS Number
53-86-1
IUPAC Name
2-[1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl-indol-3-yl]acetic acid
Molecular Weight
357.79g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4410g/cm3
Synonyms
1-(p-Chlorobenzoyl)-5-dimethylamino-2-methylindole acetic acid
Interesting facts

Interesting Facts about 2-[1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl-indol-3-yl]acetic acid

2-[1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl-indol-3-yl]acetic acid is a fascinating compound that has garnered attention in both medicinal chemistry and organic synthesis. Here are some noteworthy points about this compound:

  • Pharmacological Potential: This compound exhibits significant potential in the field of pharmaceuticals. Compounds with similar structures have been studied for their antitumor and antimicrobial properties, making it an interesting candidate for further exploration in drug development.
  • Intricate Structure: The molecular architecture of this compound is intricate, featuring an indole ring, which is a common motif in many bioactive molecules. The presence of a dimethylamino group enhances its solubility and may influence its biological activity.
  • Structural Modifications: The introduction of a 4-chlorobenzoyl moiety suggests that the compound may possess unique interaction capabilities with biological targets, and minor modifications to its structure could lead to significant changes in its efficacy.
  • Research Applications: Due to its structural resemblance to known bioactive compounds, it has been a subject of research in studies aimed at understanding the structure-activity relationship (SAR) of similar compounds.
  • Indole Derivatives: Indole and its derivatives are prevalent in nature and are known to participate in a range of biological processes, including signaling pathways and enzymatic reactions.

In summary, 2-[1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl-indol-3-yl]acetic acid represents a bridge between organic chemistry and pharmacology, demonstrating how intricate molecular designs can lead to innovative therapeutic solutions. Its ongoing exploration could reveal much more about its potential benefits and applications in medicine.

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