Amphotericin B

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Identification

Molecular formula
C47H73NO17
CAS Number
1397-89-3
IUPAC Name
[2-[17-(1-hydroxyethyl)-22-[[2-[[3-hydroxy-2-[[2-(6-methylheptanoylamino)-4-(sulfonatomethylamino)butanoyl]amino]butanoyl]amino]-4-(sulfonatomethylamino)butanoyl]amino]-3,6,9,12,15,18,23-heptaoxo-5,8-disec-butyl-11,14-bis[2-(sulfonatomethylamino)ethyl]-1,4,7,10,13,16,19-heptazacyclotricos-2-yl]ethylamino]methanesulfonate
Molecular Weight
924.08g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4300g/cm3
Synonyms
NCGC00178828-01
Interesting facts

Interesting Facts about 2-[17-(1-hydroxyethyl)-22-[[2-[[3-hydroxy-2-[[2-(6-methylheptanoylamino)-4-(sulfonatomethylamino)butanoyl]amino]butanoyl]amino]-4-(sulfonatomethylamino)butanoyl]amino]-3,6,9,12,15,18,23-heptaoxo-5,8-disec-butyl-11,14-bis[2-(sulfonatomethylamino)ethyl]-1,4,7,10,13,16,19-heptazacyclotricos-2-yl]ethylamino]methanesulfonate

This lengthy compound is a prime example of the complexity that can arise in organic chemistry, particularly in the realm of biological activity and pharmaceutical applications. Known for its extensive molecular structure, it showcases the intricate design often required for creating effective drugs. Here are some engaging facts about this compound:

  • Pharmaceutical Significance: Such complex compounds are often designed to interact with specific biological targets, potentially leading to innovative treatments. The multivalent structure may enhance its therapeutic efficacy, allowing for multiple binding sites to influence biological pathways.
  • Structure-Activity Relationship: The intricate arrangement of functional groups allows scientists to explore how structural modifications can affect the compound's activity. This exploration can lead to enhanced potency or selectivity towards particular targets.
  • Hydrophilic and Hydrophobic Balance: The presence of both hydrophobic groups, like those derived from alkyl chains, and hydrophilic groups, like sulfonates, suggests that this compound may have unique solubility characteristics. This characteristic is crucial for determining how well the drug can be delivered and absorbed in the body.
  • Potential for Innovation: Compounds with such a diverse arrangement of amino acids and functional groups could lead to new insights in drug design, particularly in the development of personalized medicine approaches.

As one researcher noted, "The complexity of this compound mirrors the intricacies of biological processes themselves, underscoring the importance of detailed chemical understanding."

In summary, this compound not only exemplifies the challenges presented in synthetic organic chemistry but also highlights the potential for breakthrough discoveries in medical science.

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