Dexamethasone phosphate

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Identification

Molecular formula
C22H29FO5P
CAS Number
55203-24-2
IUPAC Name
[2-[(17R)-17-hydroxy-10,13,16-trimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] dihydrogen phosphate
Molecular Weight
516.42g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4500g/cm3
Interesting facts

Interesting Facts about 2-[(17R)-17-hydroxy-10,13,16-trimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl dihydrogen phosphate

This compound, known for its unique structural attributes, is a phosphate ester derived from steroid frameworks. Its complex architecture provides a fascinating insight into how modifications at various positions can affect the substance's biological activity.

Structural Highlights

  • Phosphate Group: The presence of a dihydrogen phosphate moiety plays a crucial role in the compound's reactivity and interaction with biomolecules.
  • Hydroxyl Functional Group: The hydroxyl group at the 17th position influences the compound's solubility and can significantly affect its pharmacokinetics.
  • Stability Factors: The numerous methyl groups contribute to the overall stability, which is essential for maintaining biological functionality.

Biological Significance

This compound is a part of a larger class of compounds that exhibit various biological activities, potentially serving as leads in drug discovery. Some notable points include:

  • Hormonal Activity: Given its steroid-like structure, it may interact with hormone receptors, leading to diverse physiological effects.
  • Therapeutic Potential: Compounds similar to this one have shown promise in numerous therapeutic applications, including anti-inflammatory and anticancer research.
  • Research Applications: Used as a model compound, it helps chemists understand the relationship between structure and function in complex biological systems.

Quotes from the Field

As one researcher puts it: "The intricate dance of atoms in these compounds reveals secrets that nature has perfected over millions of years." This highlights the continuing exploration of chemical significance in biology.

Ultimately, the examination of this compound and its analogs offers a glimpse into the vast possibilities that exist at the intersection of organic chemistry and pharmacology.

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