Tenofovir alafenamide

ADVERTISEMENT

Identification

Molecular formula
C21H29N6O5P
CAS Number
379270-37-8
IUPAC Name
2-[2-[2-[3-acetamido-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]pentanedioic acid
Molecular Weight
476.20g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
3.2300g/cm3
Synonyms
PD042656
Interesting facts

Interesting Facts about 2-[2-[2-[3-acetamido-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]pentanedioic acid

This compound is a prime example of the complexity and beauty found within the world of chemical structures. As a member of a larger class of compounds, it showcases a multitude of functional groups, making it particularly interesting for studies in medicinal chemistry and biochemistry. Here are some noteworthy points about this compound:

  • Structural Complexity: The extensive structural design includes multiple functional groups such as acetamido, hydroxy, and phosphoryl. This variety contributes to its potential reactivity and biological activity.
  • Biological Relevance: Compounds with such intricate structures often serve as leads in drug development, particularly in targeting enzymatic pathways due to their ability to mimic natural substrates.
  • Potential Therapeutic Uses: The specific presence of pyrimidine and tetrahydrofuran rings suggests it may have applications in anti-cancer therapies, owing to their involvement in nucleic acid metabolism.
  • Synthetic Challenge: Due to its elaborate structure, synthesizing this compound can be a challenging endeavor. Synthetic chemists often develop innovative strategies to construct such multi-functionalized molecules.

This compound exemplifies the intersection of chemistry and biology, making it a fascinating subject for further research. As one delves deeper into its properties and implications, the potential for innovation in pharmaceuticals becomes evident.

ADVERTISEMENT