Diclofenac

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Identification

Molecular formula
C14H11Cl2NO2
CAS Number
15307-86-5
IUPAC Name
2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methyl-amino]-2-pyrrolidin-1-yl-ethyl]phenoxy]acetic acid
Molecular Weight
296.15g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6000g/cm3
Synonyms
Ici 204448
Interesting facts

Interesting Facts about 2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methyl-amino]-2-pyrrolidin-1-yl-ethyl]phenoxy]acetic acid

This compound is a fascinating example of how chemical modifications can lead to diverse functionalities and applications in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: The structural complexity of this compound suggests it could exhibit significant biological activity, particularly in pharmaceutical applications. Compounds like this are often explored for their potential as antidepressants or analgesics.
  • Chlorine Atoms: The presence of Cl (chlorine) atoms in its structure contributes to its chemical stability and might enhance its lipophilicity, making it more effective in crossing biological membranes.
  • Pyrrolidine Ring: The inclusion of a pyrrolidine ring is noteworthy. This moiety is known for its pharmacological significance, often appearing in compounds that interact with neurotransmitter systems.
  • Potential Applications: Given its unique structure, the compound could be used in various areas such as:
    • Drug development and screening for neuroactive agents
    • Research into selective targeting of certain receptor types
    • Exploration in the field of medicinal chemistry focused on neurodegenerative disorders
  • Structure-Activity Relationship (SAR): Understanding how each structural component affects the compound's activity is essential for optimizing its effectiveness. For instance, modifications to the ethyl or dichlorophenyl groups could yield derivatives with enhanced potency or reduced side effects.

Overall, the intricacies of 2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methyl-amino]-2-pyrrolidin-1-yl-ethyl]phenoxy]acetic acid highlight the rich interplay between chemistry and biological systems, making it a compelling topic for further research in drug design.

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