Mustine hydrochloride

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Identification

Molecular formula
C7H15Cl2N
CAS Number
55-86-7
IUPAC Name
[2-[3-[bis(2-chloroethyl)amino]phenyl]-1-carboxy-ethyl]ammonium;chloride
Molecular Weight
268.13g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6180g/cm3
Synonyms
meta-Phenylalanine mustard
Interesting facts

Interesting Facts about 2-[3-[bis(2-chloroethyl)amino]phenyl]-1-carboxy-ethyl]ammonium;chloride

This compound, often recognized for its significant role in medicinal chemistry, particularly in cancer treatment, belongs to the class of alkylating agents. Alkylating agents are known for their ability to damage DNA, effectively disrupting the reproduction of cancer cells. Here are some key points to consider:

  • Mechanism of Action: The compound works by forming covalent bonds with DNA, leading to cross-linking that halts cellular division. This makes it particularly effective against rapidly dividing cells.
  • Clinical Application: It has been used in the treatment of various cancers including lymphomas and solid tumors, showcasing its therapeutic potential in oncology.
  • Toxicity Profile: As with many chemotherapeutic agents, careful consideration is needed due to its potential side effects, which can include myelosuppression and gastrointestinal discomfort.
  • Historical Significance: The discovery of compounds like this one has contributed substantially to the field of chemotherapy, with ongoing research exploring their efficacy and ways to mitigate side effects.
  • Analytical Techniques: Various methods such as NMR spectroscopy and mass spectrometry are utilized to study and characterize this compound, allowing scientists to understand its structure and behavior better.

As the field of targeted therapy evolves, compounds like 2-[3-[bis(2-chloroethyl)amino]phenyl]-1-carboxy-ethyl]ammonium;chloride continue to be of key interest for their potential to improve cancer treatment outcomes. Ongoing research is essential to better harness their capabilities while minimizing associated risks.

As a future chemist, understanding the balance between efficacy and safety in such compounds is crucial in the development of new drugs that can change the landscape of cancer therapy.

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