Naphazoline

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Identification

Molecular formula
C14H14F3N2
CAS Number
550-99-2
IUPAC Name
2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole
Molecular Weight
246.27g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1006g/cm3
Synonyms
2-IMIDAZOLINE, 2-(m-TRIFLUOROMETHYLBENZYL)-
Interesting facts

Interesting Facts about 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole

This intriguing compound belongs to the family of imidazoles, a class of organic compounds that frequently appears in various biological systems and pharmaceutical applications. Here are some fascinating aspects of this compound:

  • Fluorine's Influence: The presence of the trifluoromethyl group (–CF3) in its structure significantly impacts the compound's electronic properties and reactivity. This group is known for enhancing the lipophilicity of compounds, often translating to improved bioavailability in medicinal chemistry.
  • Pharmacological Potential: Compounds featuring the imidazole ring are widely acknowledged for their diverse biological activities. They play vital roles in various medicinal applications, including antifungal, antibacterial, and anti-inflammatory therapies. The specific structural modifications here could yield unique therapeutics with targeted effects.
  • Structural Diversity: The imidazole ring itself is a versatile scaffold that can engage in hydrogen bonding, making it an excellent candidate for drug design. Such a diverse structure could lead to exciting derivative compounds when subjected to further chemical modifications.
  • Pivotal Role in Organic Synthesis: The synthesis of imidazole derivatives is a common task in organic chemistry, showcasing various methods such as condensation reactions, cyclization, and more. This compound exemplifies how researchers can modify reaction pathways to create tailored molecules for specific purposes.
  • Analytical Challenge: Identifying and characterizing such compounds in laboratory settings can pose interesting challenges for chemists. Techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography are often employed to elucidate their complex structures.

In summary, 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole is a compound with significant implications in chemical research and drug development. The unique arrangement of atoms not only contributes to its physical and chemical properties but also opens a doorway to exploring its potential in various scientific realms.

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