Methotrexate

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Identification

Molecular formula
C20H22N8O5
CAS Number
59-05-2
IUPAC Name
2-[[4-(3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-4H-imidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid
Molecular Weight
454.44g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4100g/cm3
Interesting facts

Interesting Facts About 2-[[4-(3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-4H-imidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid

This compound represents a fascinating intersection of organic chemistry and medicinal applications. It exhibits properties that could be leveraged in biochemistry and pharmacology. Here are some noteworthy elements regarding this compound:

  • Diverse Structure: The presence of an imidazo[1,5-f]pteridin moiety suggests potential interactions with biological targets, particularly in nucleic acid binding and enzyme inhibition systems.
  • Amino Acid Composition: The amino functionalities in the molecule may contribute to its bioactivity, mimicking natural amino acid interactions within biological systems.
  • Potential Antitumor Activity: Research indicates that similar compounds have been studied for their *antitumor* effects. Understanding the mechanism of action may lead to new cancer therapies.
  • Complexity and Synthesis: The synthetic pathway to create this compound is remarkable and may involve multiple steps, including the formation of various functional groups which can complicate purification.
  • Future Research: Scientists are continually exploring this class of compounds for new pharmaceutical applications, especially in developing treatments for diseases where current modalities are ineffective.

In summary, 2-[[4-(3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-4H-imidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid serves as a model for innovation in pharmaceutical chemistry. Its rich structural features present both challenges and opportunities in drug development.

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