Cladribine

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Identification

Molecular formula
C10H12ClN5O3
CAS Number
4291-63-8
IUPAC Name
2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Molecular Weight
285.69g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
3.0908g/cm3
Synonyms
7-Deazadenosine
Interesting facts

2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

This compound is a fascinating example of organic chemistry, particularly due to its unique structure that combines both pyrrolo-pyrimidine and tetrahydrofuran frameworks. Here are some interesting facts about this chemical compound:

  • Diverse Functionalities: One of the remarkable aspects of this compound is its ability to engage in various chemical interactions thanks to functional groups such as amino, hydroxymethyl, and diol. This diversity enhances its potential applications in medicinal chemistry.
  • Biological Potential: Compounds containing pyrrolo-pyrimidine substructures have been studied for their roles as kinase inhibitors. Kinases are crucial in cell signaling, making this compound potentially valuable in drug development for cancer and other diseases.
  • Versatile Synthetic Routes: Due to its intricate structure, the synthesis of this compound may involve multiple steps, utilizing various organic reactions. This can provide excellent opportunities for students and chemists to explore synthetic methodologies, including nucleophilic substitutions and condensation reactions.
  • Research Applications: Owing to its complex nature, this compound is of interest for research in both *pharmaceutical* and *material science*. Its properties might be explored in the development of novel therapeutics or advanced polymers.
  • Insight into Structure-Activity Relationships (SAR): Understanding how the structure of this compound relates to its biological activity is crucial. This offers a valuable lesson in pharmacology where modifications to specific parts of the molecule can significantly alter its effectiveness.

In conclusion, 2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is not only a complex chemical entity but also a potential candidate for further studies in drug design and development. As you explore this compound, think about how its unique features can inspire new innovations in chemical sciences!

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