Mitoxantrone

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Identification

Molecular formula
C22H28Cl2N4O6
CAS Number
65271-80-9
IUPAC Name
2-[[4-[bis(2-chloroethyl)amino]phenyl]methylene]propanedinitrile
Molecular Weight
421.30g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3974g/cm3
Synonyms
Malononitrile mustard
Interesting facts

Interesting Facts about 2-[[4-[bis(2-chloroethyl)amino]phenyl]methylene]propanedinitrile

This compound is a significant member of the chemical family known for its unique reactivity and potential applications in medicinal chemistry. Below are some intriguing insights regarding this complex molecule:

  • Anticancer Potential: Compounds like this one are often studied for their potential as anticancer agents. The presence of chlorinated amines can enhance the potency of drugs targeting cancer cells.
  • Mechanism of Action: The structure suggests that it could act through alkylation mechanisms, which can damage DNA and hinder replication in rapidly dividing cells, a hallmark of cancer treatment.
  • Structure-Activity Relationship (SAR): The intricate design of the molecule allows chemists to hypothesize about how modifications in the chemical structure can lead to increased efficacy or reduced side effects, paving the way for more targeted therapies.
  • Synthetic Routes: The synthesis of this compound often involves multiple steps of organic reactions, showcasing the creativity and problem-solving skills of synthetic chemists. Exploring various synthetic routes is essential for efficient large-scale production.
  • Potential Side Effects: Like many pharmaceuticals, compounds with similar structures have been noted for their potential side effects, including toxicity issues. Therefore, extensive studies are mandatory before any therapeutic application.
  • Research Applications: In addition to medicinal chemistry, this compound may be useful in academic research, particularly in exploring new drug delivery systems due to its complex nature.

In summary, 2-[[4-[bis(2-chloroethyl)amino]phenyl]methylene]propanedinitrile stands out not only for its complex molecular structure but also for its promising role in the field of pharmacology and chemical research. Its multifaceted applications make it a captivating subject for chemists and researchers alike.

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