Flufenamic Acid

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Identification

Molecular formula
C14H10ClF3NO2
CAS Number
530-78-9
IUPAC Name
2-[4-chloro-2-[[3-(trifluoromethyl)benzoyl]amino]phenyl]acetic acid
Molecular Weight
281.67g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4908g/cm3
Synonyms
BRN 2398921
Interesting facts

Interesting Facts About 2-[4-Chloro-2-[[3-(trifluoromethyl)benzoyl]amino]phenyl]acetic Acid

This compound, known for its complex structure, belongs to a class of pharmaceuticals called anti-inflammatory agents. It holds significant importance in the field of medicinal chemistry due to various properties and potential applications.

Key Properties and Applications

  • Pharmacological Significance: The presence of a chloro group and a trifluoromethyl group in its structure may contribute to its efficacy as an anti-inflammatory. Fluorinated compounds often exhibit increased metabolic stability, which is crucial for drug activity.
  • Analytical Interest: The unique structure allows for various analytical studies including NMR, mass spectrometry, and HPLC techniques, providing insight into the compound's behavior in biological systems.
  • Research Potential: Scientists are continually investigating the compound's mechanism of action and how it affects inflammatory pathways, which could lead to novel therapies for chronic inflammatory diseases.

Chemical Structure Highlights

The compound's design features several interesting aspects:

  • The amino group is essential for the biological activity, acting as a site for interaction with biological targets.
  • The trifluoromethyl group enhances lipophilicity, allowing greater permeability through biological membranes.
  • Chlorine introduces polarity, which can influence solubility and reactivity, making it a versatile compound in drug formulation.

Overall, 2-[4-chloro-2-[[3-(trifluoromethyl)benzoyl]amino]phenyl]acetic acid is a compound full of potential, and it exemplifies the intricate relationship between structure and function in medicinal chemistry.

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