Clopirac

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Identification

Molecular formula
C18H13ClN2O4
CAS Number
39184-59-5
IUPAC Name
2-[(4-chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid
Molecular Weight
369.76g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3980g/cm3
Synonyms
rebamipide
Interesting facts

Exploring 2-[(4-chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid

This intriguing compound is a derivative of quinoline, which is notable for its applications in medicinal chemistry. Its unique structure combines both aromatic and heterocyclic elements, making it a fascinating subject for chemical study. Here are some engaging facts about this compound:

  • Medicinal Potential: Compounds containing quinoline moieties have been extensively investigated for their therapeutic properties, including anti-cancer, anti-inflammatory, and anti-microbial activities.
  • Structure-Activity Relationship: The specific substitutions on the quinoline and benzoyl groups may significantly influence the biochemical activity of this compound, highlighting the importance of structure in drug design.
  • Chlorine Substitution: The presence of a chlorine atom on the benzoyl group often enhances lipophilicity, which can improve membrane permeability and, consequently, bioavailability in pharmaceutical applications.
  • Dual Functionality: This compound exhibits both amino acid characteristics due to its propanoic acid component and potential for forming various interactions with biological macromolecules, making it a versatile candidate for study.
  • Research Interest: Ongoing studies explore the synthesis of similar derivatives to evaluate their pharmacological profile and optimize therapeutic effects against various diseases.

In summary, 2-[(4-chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid showcases the intricate relationship between structure and function in chemical compounds. As researchers continue to delve into its properties, this compound may pave the way for innovative therapeutic solutions in the future.

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