Manzamine A

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Identification

Molecular formula
C37H44ClNO7
CAS Number
104195-67-1
IUPAC Name
[2-[(4R,8S,12R)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxo-ethyl] acetate
Molecular Weight
694.89g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4700g/cm3
Synonyms
SCHEMBL4354
Interesting facts

Interesting Facts about 2-[(4R,8S,12R)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxo-ethyl Acetate

This complex organic compound stands out due to its intricate structure and noteworthy applications. Here are some fascinating aspects of this compound:

  • Structural Complexity: The compound features a unique pentacyclic skeleton, characterized by five interconnected cyclic components. Such structures are often found in natural products and can exhibit diverse biological activities.
  • Fluorination: The incorporation of a fluorine atom enhances the lipophilicity of the molecule, which can improve its ability to penetrate biological membranes, making it an interesting candidate for drug development.
  • Chloroethoxy Group: The presence of a chloroethoxy substituent augments the compound's reactivity, allowing for potential chemical modifications that may lead to new derivatives with altered properties.
  • Biological Implications: Compounds with similar structural motifs have been studied for their anticancer, antiviral, and antifungal properties, highlighting the potential pharmaceutical relevance of this molecule.
  • Synthesis Challenges: The synthesis of such a complex compound typically involves multiple steps, each with specific conditions and reagents. Mastering synthetic strategies is crucial for chemists exploring similar compounds.

As one researcher aptly put it, *“The beauty of chemistry lies in the complexity of its compounds and the myriad ways we can manipulate them for beneficial purposes.”* This compound embodies that philosophy, encouraging further exploration into its properties and applications.


Through studying and understanding compounds like this, chemists gain insights into not only the molecular world but also the endless possibilities for innovation in fields such as medicinal chemistry and materials science.

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