Zidovudine

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Identification

Molecular formula
C10H13N5O4
CAS Number
30516-87-1
IUPAC Name
2-[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-6-(1,2-dihydroxyethyl)-4,5-dihydroxy-tetrahydropyran-2-carboxylic acid
Molecular Weight
267.24g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6600g/cm3
Interesting facts

Interesting Facts about 2-[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-6-(1,2-dihydroxyethyl)-4,5-dihydroxy-tetrahydropyran-2-carboxylic acid

This intriguing compound possesses a complex structure that is noteworthy for its biological importance and potential applications in pharmacology. Here are some interesting insights into this multifaceted molecule:

  • Biological Activity: The compound exhibits characteristics that can interact with various biological systems, hinting at possible roles in anti-cancer or antibiotic therapies.
  • Pyrimidine Influence: The presence of a pyrimidine ring suggests that it may interfere with nucleic acid synthesis or function, a common target for drug discovery.
  • Hydroxyl Groups: The multiple hydroxyl functional groups present in its structure contribute to its polarity and solubility, enhancing its reactivity and interactions with other biomolecules.
  • Phosphoryl Group: The phosphoryl (-PO3) moiety is vital in various biochemical processes, particularly in energy transfer. It may suggest roles in enzyme activity regulation.
  • Carboxylic Acid Moiety: The inclusion of a carboxylic acid group implies that this compound could act as a weak acid, potentially influencing its biological activity through protonation states at physiological pH.

Overall, the complexity and variety of functional groups within its structure represent a promising lead in the field of medicinal chemistry. As highlighted by chemists, "the more intricate the structure, the more profound the potential." The ongoing study and synthesis of such compounds may yield groundbreaking therapeutic discoveries.

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