Notumetinib
- Molecular formula
- C19H20ClN3O2
- CAS Number
- 7553-73-3
- IUPAC Name
- 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium
- Molecular Weight
- 391.92g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.2400g/cm3
Identification
Interesting Facts about 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium
This compound is a fascinating example of a nitrogen-containing heterocycle with interesting biological activity. Its structure features a quinazolinone ring which is known for its broad range of therapeutic properties. Below are some remarkable aspects of this compound:
- Biological Significance: The quinazolinone core is often found in pharmaceuticals due to its potential as an antimicrobial, anti-inflammatory, and anticancer agent. Compounds with this structure can disrupt various biological pathways, making them of high interest in drug discovery.
- Chlorinated Variants: The presence of a chloro substituent provides unique reactivity and may influence the compound's pharmacokinetic properties, such as absorption and metabolism.
- Ammonium Group: The trimethylammonium moiety can significantly enhance solubility in biological systems, promoting the compound's uptake in cellular environments, which is crucial for its therapeutic efficacy.
- Sulfanyl Group: The sulfanylethyl group may play a role in modulating interactions with biomolecules, offering interesting avenues for research into its function as a ligand or inhibitor in various biochemical assays.
In a research context, this compound stands at the intersection of organic chemistry and medicinal chemistry. As scientists explore its properties, they may unlock new methodologies or treatments for a variety of ailments. "Chemistry is not just a subject, it's a key to understanding the world around us," a quote that rings especially true for compounds like this one, where intricate design can lead to significant health benefits.
Continued investigation into 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium may offer valuable insights into the potential applications of quinazolinone derivatives in modern medicine.