Notumetinib

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Identification

Molecular formula
C19H20ClN3O2
CAS Number
7553-73-3
IUPAC Name
2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium
Molecular Weight
391.92g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2400g/cm3
Interesting facts

Interesting Facts about 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium

This compound is a fascinating example of a nitrogen-containing heterocycle with interesting biological activity. Its structure features a quinazolinone ring which is known for its broad range of therapeutic properties. Below are some remarkable aspects of this compound:

  • Biological Significance: The quinazolinone core is often found in pharmaceuticals due to its potential as an antimicrobial, anti-inflammatory, and anticancer agent. Compounds with this structure can disrupt various biological pathways, making them of high interest in drug discovery.
  • Chlorinated Variants: The presence of a chloro substituent provides unique reactivity and may influence the compound's pharmacokinetic properties, such as absorption and metabolism.
  • Ammonium Group: The trimethylammonium moiety can significantly enhance solubility in biological systems, promoting the compound's uptake in cellular environments, which is crucial for its therapeutic efficacy.
  • Sulfanyl Group: The sulfanylethyl group may play a role in modulating interactions with biomolecules, offering interesting avenues for research into its function as a ligand or inhibitor in various biochemical assays.

In a research context, this compound stands at the intersection of organic chemistry and medicinal chemistry. As scientists explore its properties, they may unlock new methodologies or treatments for a variety of ailments. "Chemistry is not just a subject, it's a key to understanding the world around us," a quote that rings especially true for compounds like this one, where intricate design can lead to significant health benefits.

Continued investigation into 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium may offer valuable insights into the potential applications of quinazolinone derivatives in modern medicine.

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