Pyrimethamine iodide

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Identification

Molecular formula
C21H23ClIN3OS
CAS Number
74550-97-3
IUPAC Name
2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium;iodide
Molecular Weight
458.79g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5842g/cm3
Synonyms
Ammonium, (2-((3, 4-dihydro-7-chloro-4-oxo-3-phenyl-2-quinazolinyl)thio)ethyl)trimethyl-, iodide
Interesting facts

Interesting Facts about 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium iodide

This compound is a fascinating example of a quaternary ammonium salt, which plays a significant role in chemical synthesis and biological applications. Here are some noteworthy aspects:

  • Quaternary Ammonium Compounds: These compounds are known for their antibacterial and antifungal properties, making them valuable in medical and industrial fields. Their *cationic* nature allows them to interact well with negatively charged surfaces, such as cell membranes.
  • Pharmacological Potential: The structure of this compound indicates a potential for pharmacological activity, particularly due to the presence of the quinazoline ring. Quinazolines are a pivotal class of compounds in drug development, often exhibiting anti-cancer, anti-inflammatory, and anti-viral properties.
  • Synthesizing Challenges: The synthesis of this compound requires careful manipulation of various reagents and conditions, showcasing the intricate nature of creating compounds with specific biological functionalities. Chemists often need to monitor reaction conditions meticulously to ensure desired outcomes.
  • Research Importance: Research on compounds like this is ongoing, with scientists investigating how modifications to the molecular structure can enhance bioactivity and reduce toxicity. Studies often aim to optimize the balance between efficacy and safety.
  • Structural Diversity: The addition of different functional groups, such as the chlorinated phenyl and sulfonium components, not only expands the diversity of synthetic pathways but also allows for the exploration of multifaceted biological targets.

In conclusion, 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylethyl-trimethyl-ammonium iodide is more than just a chemical compound; it's a gateway into the world of medicinal chemistry, where nuances in molecular design can lead to groundbreaking therapies. As researchers continue to delve into the properties and potential uses of this unique compound, it stands as a reminder of the complexities and possibilities present within the realm of chemistry.

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