Dexamethasone phosphate

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Identification

Molecular formula
C22H30FO8P
CAS Number
55203-24-2
IUPAC Name
[2-[(8S,9R,10S,11S,13S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] dihydrogen phosphate
Molecular Weight
472.42g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4700g/cm3
Synonyms
PDSP2_001630
Interesting facts

Interesting Facts about 2-[(8S,9R,10S,11S,13S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] Dihydrogen Phosphate

This complex compound, commonly recognized in the field of biochemistry and medicinal chemistry, has garnered significant attention due to its multifaceted roles in various biochemical processes. Here are some compelling aspects worth exploring:

  • Pharmacological Significance: The presence of fluoride and hydroxyl groups lends this compound unique properties, making it a potential candidate for therapeutic applications, particularly in hormone regulation and cancer therapy.
  • Stereochemistry: With multiple chiral centers, the compound's stereochemistry plays a crucial role in determining its biological activity. The specific configuration of its stereocenters can influence how it interacts with biological targets, underscoring the importance of stereochemistry in drug design.
  • Structural Complexity: Its intricate structure, characterized by a cyclopenta[a]phenanthrene backbone, not only provides stability but may also facilitate interactions with lipid membranes, enhancing its bioavailability.
  • Phosphate Group Role: The dihydrogen phosphate group is vital in biochemical signaling pathways, often acting as a crucial link in phosphorylation processes that regulate numerous cellular functions.

As a chemical scientist, it is fascinating to consider how compounds such as this can lead to breakthroughs in our understanding of complex biological systems. Research into its properties and mechanisms can pave the way for the development of innovative therapeutic agents. As the saying goes, "The more we know, the better we can innovate." Understanding the nuances of such compounds is crucial in the ongoing pursuit of effective treatments in modern medicine.

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