Melphalan

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Identification

Molecular formula
C13H18Cl2N2O2
CAS Number
148-82-3
IUPAC Name
2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
Molecular Weight
305.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2070g/cm3
Appearance
depending on the clinical preparation.
Synonyms
Sarcolysin
Interesting facts

Interesting Facts About 2-Amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic Acid

2-Amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid, often referred to in the context of medicinal chemistry, is a curious compound with intriguing properties and applications. Here are some fascinating insights:

  • Chemotherapeutic Agent: This compound is notable for its role as a potential anticancer agent. Its structure suggests a capacity for targeting rapidly dividing cells, a hallmark of many cancer therapies.
  • Mechanism of Action: The presence of the bis(2-chloroethyl)amino moiety is relevant, as it is known to form highly reactive species that can lead to DNA cross-linking, thereby inhibiting cell division.
  • Structural Complexity: The compound exemplifies a sophisticated design with multiple functional groups, enabling interactions that are vital in pharmacology. The balance between both amine and carboxylic acid groups contributes to its chemical behavior.
  • Importance of Chirality: As an amino acid derivative, this compound also exhibits chirality, with implications for its biological interactions and specificity in drug design.
  • Research Applications: Ongoing research explores its potential roles not only in cancer treatment but also in addressing other conditions where cellular proliferation is a concern.

In summary, 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid serves as a prime example of how structure determines function in medicinal chemistry. Understanding its unique properties is crucial for the development of effective therapeutic strategies.

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