2-Amino-8-phosphono-octanoic acid

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Identification

Molecular formula
C8H18NO5P
CAS Number
1492-51-1
IUPAC Name
2-amino-8-phosphono-octanoic acid
Molecular Weight
235.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4610g/cm3
Synonyms
2-Amino-8-phosphonooctanoic acid
Interesting facts

Interesting Facts About 2-Amino-8-phosphono-octanoic Acid

2-Amino-8-phosphono-octanoic acid, often abbreviated as APO, is a fascinating chemical compound that belongs to the family of amino acids and phosphonates. It has attracted significant attention in various scientific fields due to its unique properties and applications.

Key Features of 2-Amino-8-phosphono-octanoic Acid:

  • Neurotransmission Modulator: This compound acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, which plays a crucial role in excitatory neurotransmission in the brain. Its ability to modulate these receptors makes it a valuable tool in neuropharmacology.
  • Possibility in Pharmacology: Research indicates that APO may have potential therapeutic applications in treating neurological disorders, such as epilepsy and neurodegenerative diseases, by modulating synaptic transmission.
  • Synthesis Importance: The synthesis of 2-amino-8-phosphono-octanoic acid represents a significant milestone in organic chemistry due to its complex structure, which includes both amino acid and phosphonate functionalities.
  • Use in Research: This compound is frequently utilized in various experimental setups, particularly in studies focusing on calcium signaling and synaptic plasticity, highlighting its importance in furthering our understanding of neurobiology.

Furthermore, its role as a secondary messenger in cellular signaling processes underscores its significance in biochemistry. As researchers continue to explore its mechanisms and effects, 2-amino-8-phosphono-octanoic acid stands as an exemplary case of how amino acids can be intricately linked with phosphorus to influence biological systems.

In summary, the exploration of 2-amino-8-phosphono-octanoic acid not only advances our knowledge in chemical synthesis and pharmacological applications but also opens new avenues for understanding complex biochemical pathways in living organisms.

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