Tenofovir

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Identification

Molecular formula
C9H14N5O4P
CAS Number
201341-05-1
IUPAC Name
2-amino-9-[2-hydroxy-6-(hydroxymethyl)-2-thioxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-3H-purin-6-one
Molecular Weight
287.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.2000g/cm3
Interesting facts

Exploring 2-Amino-9-[2-hydroxy-6-(hydroxymethyl)-2-thioxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-3H-purin-6-one

The compound 2-amino-9-[2-hydroxy-6-(hydroxymethyl)-2-thioxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-3H-purin-6-one, often abbreviated for convenience, represents a complex structure with intriguing features that make it a subject of interest in the fields of medicinal chemistry and biochemistry.

Key Characteristics

  • Novel Biological Activity: This compound is part of a class of phosphorus-containing heterocycles known for their diverse biological activities, including potential anticancer and antiviral properties.
  • Possession of Multiple Functional Groups: The molecule showcases various functional groups such as amino, hydroxy, and thioxo, which are known to influence its chemical reactivity and interaction with biological systems.
  • Complex Structure: The intricate arrangement of rings, particularly the bicyclic phosphorus analogs, can lead to unique mechanisms of action compared to simpler drugs.

As a research-oriented compound, it embodies the idea that "nature's complexity often leads to novel therapeutic pathways." Understanding its mechanism of action might open new avenues for drug development, particularly in targeting resistant cancer types. The structure's elegance, paired with its biological potential, showcases the beauty and intricacy of molecular design.

Research and Applications

This compound could be part of ongoing studies aimed at:

  • Designing new pharmaceuticals that effectively engage with specific biological targets.
  • Exploring its potential as a scaffold for creating analogs with enhanced activity or selectivity.
  • Investigating its pharmacological properties through in vitro and in vivo assays.

In conclusion, the exploration of 2-amino-9-[2-hydroxy-6-(hydroxymethyl)-2-thioxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-3H-purin-6-one is more than a chemical curiosity; it represents a promising frontier in the quest for innovative therapeutic strategies.

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