2'-Deoxythymidine 5'-(dihydrogen phosphate)

ADVERTISEMENT

Identification

Molecular formula
C9H15N2O8P
CAS Number
10049-83-9
IUPAC Name
[2-aminoethoxy(hydroxy)phosphoryl] [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
Molecular Weight
402.18g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.2900g/cm3
Synonyms
4-amino-1-{5-o-[{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]pentofuranosyl}pyrimidin-2(1h)-one
Interesting facts

Interesting Facts about [2-aminoethoxy(hydroxy)phosphoryl] [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

This compound is a fascinating example of organic phosphorus chemistry and exhibits potential biological significance. It encapsulates a harmonious blend of both amino acids and nucleoside derivatives, which piques the interest of many chemists and biochemists alike.

Key Features

  • Biological Relevance: The presence of pyrimidine and amino functionalities suggests potential roles in nucleotide metabolism and biological pathways. Compounds like this are often studied for their interactions with enzymes and receptors.
  • Phosphorylation: The phosphoryl group within this compound is involved in energy transfer processes in biological systems, mirroring the structural features of ATP, an essential energy currency of all living cells.
  • Synthetic Applications: This compound may serve as an important intermediate in the synthesis of more complex biomolecules. Its unique structure allows for various chemical modifications, paving the way for the development of novel pharmaceutical agents.

Notably, the dual role of this compound as both a phospho- and amino- derivative showcases the intricate balance within biological systems where nucleophilic substitutions are crucial for metabolic processes. As a chemistry student or scientist, examining how such compounds function within larger biological contexts can lead to significant discoveries in drug development and therapeutic interventions.

Understanding the reactivity and properties of this compound may provide insights into the mechanisms of action at the molecular level, blending synthetic organic chemistry with biochemistry in a symphony of innovative research.

ADVERTISEMENT