Losartan
- Molecular formula
- C22H23ClN6O
- CAS Number
- 114798-26-4
- IUPAC Name
- [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
- Molecular Weight
- 422.92g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.2780g/cm3
- Synonyms
- losartan
Identification
Interesting Facts about 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
This compound, known as 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol, is a fascinating molecule that showcases the intricate relationship between structure and biological activity.
Chemical Features
- Complex Structure: The compound consists of a fused imidazole ring and a tetrazole group, both of which contribute unique properties and functionalities.
- Tetrazole Moiety: The presence of the tetrazole group often leads to increased solubility and bioactivity, playing a crucial role in pharmaceuticals.
- Chlorinated Carbon: The chlorine substitution may enhance the compound's reactivity and can influence its interaction with biological targets.
Applications
Due to its unique structural characteristics, this compound has potential applications in various fields, especially in medicinal chemistry:
- Pharmaceutical Development: Its ability to interact with biological macromolecules suggests it could lead to new therapeutic agents.
- Research Chemical: It can serve as a tool compound in research, helping scientists understand the mechanisms of disease at a molecular level.
Recognition
Compounds like this one often undergo rigorous evaluation:
- Preclinical Studies: Important for assessing safety and efficacy prior to human trials.
- Structure-Activity Relationship (SAR) Studies: Investigating how modifications to the compound can affect its biological activity.
The complexity and potential of 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol makes it an exciting subject of study. As scientists continue to explore the diverse applications of such compounds, they open up pathways for innovative drug development and a deeper understanding of chemical interactions within biological systems.