Chlorambucil

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Identification

Molecular formula
C14H19Cl3N2
CAS Number
305-03-3
IUPAC Name
2-chloro-N-(2-chloroethyl)-N-[(2-chlorophenyl)methyl]ethanamine
Molecular Weight
304.68g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3000g/cm3
Synonyms
o-Chloro-dcba
Interesting facts

Interesting Facts about 2-chloro-N-(2-chloroethyl)-N-[(2-chlorophenyl)methyl]ethanamine

2-chloro-N-(2-chloroethyl)-N-[(2-chlorophenyl)methyl]ethanamine, often referred to as a chlorinated amine compound, holds significant interest in various fields, particularly in medicinal chemistry and pharmaceuticals.

Key Highlights:

  • Pharmacological Relevance: This compound has been explored for its potential role in therapeutic applications, especially in treating certain types of cancers due to its mechanism of action involving cell cycle interference.
  • Structure Activity Relationship (SAR): Its unique chlorinated structure allows scientists to study how modifications can enhance efficacy or reduce toxicity, showcasing the importance of chemical structure in drug design.
  • Mechanism of Action: Investigations indicate that the compound may behave as an alkylating agent, targeting DNA and ultimately leading to apoptosis in malignant cells.
  • Environmental Impact: As a chlorinated compound, it raises concerns regarding environmental persistence and bioaccumulation, stimulating studies into safer disposal methods and its ecological footprint.

Moreover, compounds like this one are crucial in the ongoing quest for new medications to combat resistant strains of diseases. As stated by many researchers in the field, “Understanding the chemistry behind these compounds paves the way for innovative therapeutic solutions.”

In addition to its medicinal qualities, the synthesis of 2-chloro-N-(2-chloroethyl)-N-[(2-chlorophenyl)methyl]ethanamine also serves as a valuable exercise in organic chemistry, illustrating key principles like substitution reactions and reaction mechanism elucidation. As science continues to evolve, such compounds exemplify the delicate balance of innovation and caution necessary in modern drug development.

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