Colchicine

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Identification

Molecular formula
C22H25ClNO6
CAS Number
64-86-8
IUPAC Name
2-chloro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular Weight
399.44g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6600g/cm3
Synonyms
Chlorcolchicine
Interesting facts

Interesting Facts about 2-chloro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

The compound 2-chloro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide is a fascinating compound that demonstrates the complexity and diversity of organic chemistry. Here are some intriguing insights about this compound:

  • Structural Diversity: This compound contains multiple functional groups and a unique bicyclic structure, which contribute to its potential biological activities. The presence of the chloro group introduces reactivity that can be exploited in synthetic chemistry.
  • Biological Relevance: Compounds with similar structural motifs have been researched for their roles in medicinal chemistry. They may exhibit interesting pharmacological properties, such as anti-inflammatory or anticancer activities, making them worthwhile candidates for drug discovery.
  • Complex Synthesis: The synthesis of compounds like this one often requires multi-step reactions, showcasing the intricacies of organic synthesis. The manipulation of various substituents can lead to profound changes in reactivity and biological activity.
  • Conformational Flexibility: Due to its multi-ring structure and substituents, this compound may exhibit unique conformational isomerism. This can affect how the compound interacts with biological targets, impacting its efficacy in medicinal applications.
  • Chirality and Specificity: The stereochemistry of the compound is significant as well. The (7S) configuration can play a crucial role in determining the biological activity, as many biological systems are sensitive to the chirality of the molecules they interact with.

As a compound rich in chemical potential, 2-chloro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide serves as a reminder of the depths of organic chemistry and its ability to weave complex structures that may lead to groundbreaking discoveries in medicine and beyond.

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