Amsacrine

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Identification

Molecular formula
C21H19ClN2O
CAS Number
51264-14-3
IUPAC Name
2-chloroethyl-[3-[(6-chloro-2-methoxy-acridin-9-yl)ammonio]propyl]ammonium;dichloride
Molecular Weight
458.82g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3750g/cm3
Synonyms
ICR-191A
Interesting facts

Interesting Facts about 2-chloroethyl-[3-[(6-chloro-2-methoxy-acridin-9-yl)ammonio]propyl]ammonium;dichloride

This compound, with its complex structure, is a derivative of acridine, a compound known for its role in various biological activities. It features a chloroethyl group attached to a nitrogen atom, which is quite significant when considering its applications in medicinal chemistry. Here are some key highlights:

  • Biological Activity: Compounds containing acridine derivatives are often studied for their antitumor and antimicrobial properties. This particular compound may exhibit similar activities, making it a subject of interest in cancer research.
  • Synergistic Potential: Many acridine-related compounds are found to work synergistically with other treatments, enhancing their efficacy. By modifying functional groups, compounds can be tailored for improved therapeutic effects.
  • Use in Drug Development: The presence of positively charged ammonium groups can enhance the affinity of the compound for cellular membranes, potentially improving its uptake and action within cells.
  • Chlorine Atoms: The chlorine substitutions on the acridine ring may affect the compound’s reactivity and biological behavior, often contributing to the mechanism of action against various types of cancer cells.

As stated in the literature, "acridine derivatives continue to represent a significant area of interest in pharmacology, particularly in the design of new anticancer agents." This underscores the importance of understanding the chemical properties and biological implications of compounds like this one.

In summary, this compound is not merely a complex molecule but a potential catalyst for groundbreaking advancements in cancer treatment, emphasizing the beauty and utility of chemistry in medicine.

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