Loperamide

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Identification

Molecular formula
C29H33ClN2O2
CAS Number
34552-83-5
IUPAC Name
2-(diethylamino)ethyl 2-ethoxy-2,2-diphenyl-acetate
Molecular Weight
477.59g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1140g/cm3
Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 2-ethoxy-2,2-diphenyl-acetate

2-(Diethylamino)ethyl 2-ethoxy-2,2-diphenyl-acetate, also known for its various applications in medicinal chemistry, presents a fascinating profile worth exploring. Here are several engaging aspects of this intriguing compound:

  • Pharmacological Potential: This compound can serve as a scaffold in drug design, due to the presence of both the diethylamino and diphenyl groups, which may enhance its pharmacokinetic properties.
  • Mechanism of Action: Research suggests that derivatives of this compound might interact with neurotransmitter systems, potentially leading to psychoactive effects, grounding its relevance in neuropharmacology.
  • Synthesis Techniques: The synthesis of this compound often involves a combination of amine alkylation and esterification reactions, presenting an interesting challenge for organic chemists.
  • Structure-Activity Relationship (SAR): Understanding the SAR is critical for determining the biological activity and improving the efficacy of similar compounds. The variations in substituents can lead to significant changes in activity.
  • Versatile Applications: Beyond medicinal uses, compounds similar to this one have been explored in materials science and pesticides, showcasing their versatility and importance in various fields.

In conclusion, 2-(diethylamino)ethyl 2-ethoxy-2,2-diphenyl-acetate is more than just a chemical formula; its complex structure offers invaluable insights into potential therapeutic and industrial applications, reflecting the beauty and utility of organic chemistry.

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