Chlordiazepoxide
- Molecular formula
- C16H14ClN3O2
- CAS Number
- 58-25-3
- IUPAC Name
- but-2-enedioic acid;7-chloro-1-[3-(4-methylpiperazin-1-yl)propyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
- Molecular Weight
- 299.75g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.3400g/cm3
Identification
Interesting Facts about But-2-enedioic Acid; 7-Chloro-1-[3-(4-methylpiperazin-1-yl)propyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
But-2-enedioic acid, commonly known as fumaric acid, when paired with the complex benzodiazepine structure, presents a fascinating interplay of biochemical and pharmacological attributes. Here are some noteworthy aspects:
- Dual functionality: The presence of both a dicarboxylic acid (but-2-enedioic acid) and a benzodiazepine moiety introduces unique properties that can be utilized in various therapeutic applications.
- Pharmaceutical relevance: The benzodiazepine component is known for its anxiolytic, sedative, and anticonvulsant properties, making this compound particularly interesting for the development of new medications.
- Structure-activity relationship: The modification of the benzodiazepine core and the incorporation of piperazine groups can dramatically influence binding affinities and selectivity for neurotransmitter receptors, such as GABAA. This makes compound optimization a vital area of research.
- Chemical stability: The stability of such complex compounds under physiological conditions can vary, thus understanding their reactivity and metabolism is crucial for effective application in drug formulation.
- Role in cellular metabolism: But-2-enedioic acid itself is a natural intermediate in the citric acid cycle, contributing to energy production in living organisms and enhancing the study of metabolism in biochemistry.
Incorporating structural diversity through different substituents can lead to a myriad of derivatives, each with distinct biological activities. This emphasizes the need for continued exploration in the synthesis and application of such compounds in medicinal chemistry.
As scientists delve deeper into the potential of these compounds, they often quote the old adage, "Structure determines function." This rings especially true in pharmacology, where even a slight change in structure can lead to vastly different effects in biological systems.