Amphotericin B

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Identification

Molecular formula
C47H73NO17
CAS Number
1397-89-3
IUPAC Name
2-hydroxy-2-[20,24,28,30-tetrahydroxy-18-[2-hydroxy-1-[[3,7,11,13-tetrahydroxy-12-[(7-hydroxy-9-methoxy-4,4,6,8,8-pentamethyl-5,9-dioxo-non-2-enoyl)amino]-2,6,8,10,14-pentamethyl-pentadec-8-enoyl]amino]propyl]-19,23,25,27,29,34-hexamethyl-13,16-dioxo-17,36-dioxa-14-azabicyclo[30.3.1]hexatriaconta-3,5,9,11,22,26-hexaen-15-yl]acetic acid
Molecular Weight
924.09g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6809g/cm3
Appearance
may vary slightly depending on the form, such as crystalline or lyophilized powder, and it is typically available in powder form for pharmaceutical use.
Interesting facts

Exploring the Multifaceted Nature of 2-hydroxy-2-[20,24,28,30-tetrahydroxy-18-[2-hydroxy-1-[[3,7,11,13-tetrahydroxy-12-[(7-hydroxy-9-methoxy-4,4,6,8,8-pentamethyl-5,9-dioxo-non-2-enoyl)amino]-2,6,8,10,14-pentamethyl-pentadec-8-enoyl]amino]propyl]-19,23,25,27,29,34-hexamethyl-13,16-dioxo-17,36-dioxa-14-azabicyclo[30.3.1]hexatriaconta-3,5,9,11,22,26-hexaen-15-yl]acetic acid

This intricate compound boasts a highly complex structure, making it a fascinating subject of study within the field of bioorganic chemistry. Here are some intriguing facts about this unique molecule:

  • Natural Analogues: Compounds with similar structures often exhibit important biological activities, which makes them valuable in pharmacology and medicinal chemistry.
  • Functional Groups: The presence of multiple hydroxyl (-OH) groups suggests that this compound could engage in hydrogen bonding, enhancing its solubility and reactivity in various environments.
  • Potential Applications: The detailed substitutions hint at potential utility in drug design, particularly for creating targeted therapies in treating diseases linked to metabolic and hormonal processes.
  • Structural Complexity: With a myriad of functional groups and its unique bicyclic framework, this compound is a stellar example of molecular diversity, showcasing how small changes in a structure can drastically alter biological function.

Moreover, chemists are particularly fascinated by compounds such as this due to their potential as lead compounds in the development of new pharmaceuticals. Their ability to mimic biological pathways provides critical insight into drug-receptor interactions and metabolic pathways.

As we continue to advance in analytical techniques and structural elucidation, the study of compounds like 2-hydroxy-2-[20,24,28,30-tetrahydroxy-18-[2-hydroxy-1-[[3,7,11,13-tetrahydroxy-12-[(7-hydroxy-9-methoxy-4,4,6,8,8-pentamethyl-5,9-dioxo-non-2-enoyl)amino]-2,6,8,10,14-pentamethyl-pentadec-8-enoyl]amino]propyl]-19,23,25,27,29,34-hexamethyl-13,16-dioxo-17,36-dioxa-14-azabicyclo[30.3.1]hexatriaconta-3,5,9,11,22,26-hexaen-15-yl]acetic acid opens promising opportunities for novel discoveries in therapeutic applications and biochemical research.

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