2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)acetamide

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Identification

Molecular formula
C6H12F3NO1Si1
CAS Number
24589-78-4
IUPAC Name
2,2,2-trifluoro-N-methyl-N-trimethylsilyl-acetamide
Molecular Weight
199.27g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.0110g/cm3
Synonyms
24589-78-4
Interesting facts

Interesting Facts about 2,2,2-Trifluoro-N-methyl-N-trimethylsilyl-acetamide

2,2,2-Trifluoro-N-methyl-N-trimethylsilyl-acetamide is a compound that garners interest due to its unique chemical properties and versatile applications in various fields. Here are some notable points that highlight its significance:

  • Fluorination Advantage: The presence of trifluoromethyl groups in this compound enhances its reactivity and stability, making it a valuable intermediate in organic synthesis.
  • Role in Synthesis: This compound serves as a reliable reagent in the formation of various carbon–carbon bonds. It is particularly useful for preparing fluorinated compounds, which are important in pharmaceuticals and agrochemicals.
  • Effect on Biological Activity: The incorporation of fluorine often alters biological properties, improving the metabolic stability of drugs and enhancing their efficacy. This compound's derivatives have been evaluated for potential therapeutic use.
  • Analytical Chemistry: Its unique structure makes it an intriguing choice for mass spectrometry and NMR studies, providing insights into molecular behavior.
  • Environmental Considerations: The trifluoroacetyl moiety in the compound raises questions regarding environmental impact; thus, it's essential to study its degradation pathways and toxicity to develop safer alternatives.

In conclusion, 2,2,2-trifluoro-N-methyl-N-trimethylsilyl-acetamide exemplifies the fascinating interplay between structure and function in chemical compounds. Its broader implications in research and industry make it a compelling subject of study for chemists and scientists alike. As we explore its potential, it remains essential to address both its synthetic advantages and environmental considerations.

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