Sitagliptin

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Identification

Molecular formula
C6H5Cl2NO2
CAS Number
486460-32-6
IUPAC Name
2,3-dihydroxypropyl 2-(3-chloro-2-methyl-anilino)pyridine-3-carboxylate
Molecular Weight
523.33g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6670g/cm3
Synonyms
CLONIXERIL
Interesting facts

Interesting Facts about 2,3-Dihydroxypropyl 2-(3-Chloro-2-methyl-anilino)pyridine-3-carboxylate

The compound 2,3-dihydroxypropyl 2-(3-chloro-2-methyl-anilino)pyridine-3-carboxylate belongs to a fascinating category of organic compounds known as pyridine derivatives. Pyridine is a six-membered aromatic ring with a nitrogen atom, and its derivatives often exhibit unique chemical properties that can be harnessed in various applications.

Applications and Importance

This compound holds significance in several fields:

  • Pharmaceutical Industry: Pyridine derivatives are often implemented in pharmaceutical formulations due to their effectiveness in modifying biological activities.
  • Agrochemicals: Compounds like this one may serve as precursors or active ingredients in pesticides and herbicides, contributing to agricultural productivity.
  • Research Chemical: The compound is often used in studies aimed at understanding drug interactions and mechanisms of action.

Chemical Properties

From a chemical perspective, 2 and 3 hydroxy groups in this compound indicate its potential as a polyfunctional agent. Properties of hydroxyl groups lead to:

  • Increased Solubility: Hydroxyl groups can enhance solubility in water, making the compound suitable for a variety of organic reactions.
  • Hydrogen Bonding: The presence of hydroxyl groups allows for extensive hydrogen bonding, influencing the compound's behavior in different environments.

Structural Aspects

The overall structural composition of this compound allows it to exhibit interesting interactions. For the synthetic chemist, understanding the structure-activity relationship (SAR) is crucial. As expressed by some chemists, “The structure of a compound is a language in itself; it narrates its behavior in chemical reactions.” This means:

  • The 3-chloro substitution introduces distinct electronic effects.
  • Anilino additions aid in enhancing biological potency.

In summary, 2,3-dihydroxypropyl 2-(3-chloro-2-methyl-anilino)pyridine-3-carboxylate represents a noteworthy example of how complex organic structures can lead to a multitude of useful applications and scientific explorations. Its chemical nuances make it a significant focus for both pharmaceutical and industrial research.

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