Chloroquine phosphate ester

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Identification

Molecular formula
C25H26ClN3O3
CAS Number
50-63-5
IUPAC Name
2,3-dihydroxypropyl 2-[(7-chloro-4-quinolyl)amino]benzoate
Molecular Weight
506.90g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4500g/cm3
Synonyms
glafenine
Interesting facts

Interesting Facts about 2,3-Dihydroxypropyl 2-[(7-Chloro-4-quinolyl)amino]benzoate

2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolyl)amino]benzoate is a fascinating compound that bridges the fields of medicinal chemistry and pharmacology. Here are some noteworthy points about this intriguing molecule:

  • Therapeutic Potential: This compound is part of a class of compounds known for their antimicrobial properties. It has been studied for its potential use in treating various bacterial infections, showcasing the role of quinoline derivatives in drug discovery.
  • Mechanism of Action: The presence of the 7-chloro-4-quinolyl group is key to its biological activity. This moiety interacts with specific enzymes or proteins in bacteria, leading to inhibition of their growth.
  • Structure-Activity Relationship: The modification of the hydroxyl groups in the propyl chain can alter the bioactivity of the compound significantly, providing insights into how structural changes can enhance or diminish the efficacy of potential drugs.
  • Multi-Functional Applications: Beyond its antimicrobial activity, the structural components suggest that this compound may have utility in other fields, such as anti-inflammatory therapies or as dye precursors in chemical industries.
  • Synthetic Routes: The synthesis of this compound often involves several steps, including nucleophilic substitution and selective functional group modifications. Understanding these pathways is crucial for optimizing production methods.

Overall, 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolyl)amino]benzoate exemplifies the intricate relationship between chemical structure and biological activity, making it a compelling topic for both research and educational discourse in the field of chemistry.

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