Quinoline antibiotic analog

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Identification

Molecular formula
C20H17F3N2O5
CAS Number
850140-72-6
IUPAC Name
2,3-dihydroxypropyl 2-[[8-(trifluoromethyl)-4-quinolyl]amino]benzoate
Molecular Weight
413.37g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4300g/cm3
Appearance
can vary slightly depending on the purity and form (e.g., hydrate or anhydrous) of the particular sample being observed.
Synonyms
floctafenine
Interesting facts

Interesting Facts about 2,3-Dihydroxypropyl 2-[[8-(trifluoromethyl)-4-quinolyl]amino]benzoate

This compound represents a fascinating intersection of medicinal chemistry and organic synthesis, notably due to its unique structural features. Here are some engaging insights into its properties and potential applications:

  • Quinoline Backbone: The presence of a quinoline moiety is significant, as compounds containing this structure are often noted for their biological activity, especially in developing pharmaceuticals.
  • Trifluoromethyl Group: The trifluoromethyl (–CF3) group is known for enhancing the lipophilicity of compounds, which can improve their bioavailability and pharmacological properties.
  • Dual Hydroxy Groups: The two hydroxy groups (–OH) in the molecule can participate in various hydrogen bonding interactions, potentially influencing the compound's solubility and reactivity.
  • Drug Development: Given its multi-functional nature, this compound could serve as a lead structure in drug design, particularly in fields targeting anti-cancer or anti-inflammatory activities.
  • Research Potential: Studies on the synthesis and modification of similar compounds are ongoing, with research often revolving around improving efficacy and reducing side effects of therapies.

As with many chemical compounds, the combination of functional groups present within 2,3-dihydroxypropyl 2-[[8-(trifluoromethyl)-4-quinolyl]amino]benzoate opens many avenues for scientific exploration. Understanding how such compounds interact with biological systems is essential for the advancement of medicinal chemistry.

In the words of famous chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound is a prime example of how innovative thinking in chemistry can lead to the development of potentially life-changing drugs.

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