Uracil-6-carboxylic acid

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Identification

Molecular formula
C5H2N2O4
CAS Number
617-86-7
IUPAC Name
2,4-dioxo-1H-pyrimidine-6-carboxylic acid
Molecular Weight
154.08g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.1400g/cm3
Synonyms
Orotic acid
Interesting facts

Exploring 2,4-Dioxo-1H-pyrimidine-6-carboxylic Acid

2,4-Dioxo-1H-pyrimidine-6-carboxylic acid, commonly referred to as a pyrimidine derivative, is a fascinating compound with noteworthy characteristics. This compound belongs to a class of heterocyclic organic compounds that play essential roles in biochemistry and medicinal chemistry. Below are some engaging facts about this intriguing compound:

  • Biological Significance: Pyrimidine derivatives are fundamental components of nucleic acids, like DNA and RNA. The presence of dioxo groups adds additional functionality, possibly influencing interactions with biological targets.
  • Potential Therapeutic Uses: Research has indicated that derivatives of pyrimidine can exhibit antimicrobial and antitumor properties. The compound's structure suggests it may be a candidate for developing new pharmaceuticals.
  • Synthetic Versatility: The synthesis of 2,4-dioxo-1H-pyrimidine-6-carboxylic acid can be approached through various synthetic routes, making it a convenient target for organic chemists looking to explore heterocyclic chemistry.
  • Chemical Reactivity: The carboxylic acid functional group can undergo typical reactions, such as esterification and amide formation, allowing for the derivatization of this compound and the formation of a range of new derivatives.

Furthermore, the compound’s reactions and transformations can reveal unparalleled insights into the chemistry of heterocycles, captivating both students and experienced chemists alike. "Understanding how different structures influence biochemical activity is one of the most challenging yet rewarding aspects of chemical research." This emphasizes the excitement of studying compounds like 2,4-dioxo-1H-pyrimidine-6-carboxylic acid that stand at the intersection of chemistry, biology, and medicine.

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